REACTIVE OXYGEN SPECIES-RESPONSIVE NANOCOCKTAIL WITH SELF-AMPLIFICATED DRUG RELEASE FOR EFFICIENT CO-DELIVERY OF PACLITAXEL/CUCURBITACIN B AND SYNERGISTIC TREATMENT OF GASTRIC CANCER

Application of drug combinations is a powerful strategy for the therapy of advanced gastric cancer.However, the clinical use of such combinations is greatly limited by the occurrence of severe systemic toxicity.Although polymeric-prodrug-based nanococktails can significantly reduce toxicity of drugs, they have been shown to have low intracellular d

In order to further improve the equity financing efficiency of listed companies in strategic emerging industries, this paper selects relevant data grace m801 of 208 listed companies in strategic emerging industries from 2014 to 2018, and calculates the changes in scale efficiency, pure technical efficiency and total factor productivity through the

In our daily lives, we often have to quickly estimate the emotions of our conspecifics in order to have successful social interactions.While this estimation process seems quite easy when we are ourselves in a neutral or equivalent emotional state, it has recently been shown that in case of incongruent emotional states between ourselves and the othe

Skin ageing is a complex process that is determined by both intrinsic and extrinsic factors, which leads to a progressive loss of structure and function.There is extensive evidence indicating that oxidative stress induced by reactive oxygen species plays an important role in the process of human skin ageing.Mitochondria are the major source of cell

In this paper, a novel Pixel-Voxel network is proposed for dense 3D semantic mapping, which can perform dense 3D mapping while simultaneously recognizing and labelling the semantic category each point in the 3D map.In our approach, we fully leverage the advantages of different modalities.That is, the PixelNet can learn the high-level contextual inf